By Özge ÖzkayaMapping the Cellular Landscape of Endometriosis and Progesterone Resistance
By Özge Özkaya
A new study published in he peer-reviewed scientific journal Clinical and Translational Medicine offers a single-cell transcriptomic atlas of peritoneal endometriosis, deep-infiltrating endometriosis (DIE), and ovarian endometriosis, shedding light on the cellular heterogeneity and potential mechanisms driving progesterone resistance across subtypes. Researchers from the Department of Obstetrics and…
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Could Traditional Chinese Medicine Treat Endometriosis?
By Özge Özkaya
Tetramethylpyrazine, a compound derived from a herb and used in traditional Chinese medicine could be a promising drug candidate to treat endometriosis. This is according to a new study by Dr. Shenghui Huang and colleagues published in the scientific journal…
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By Bahar YukselVitamin A interrupts epithelial-mesenchymal transition in endometriosis
By Bahar Yuksel
The mechanism underlying the endometriosis formation is still not clear. Recent studies are focusing on the effect of retinoic acid and IL6 on epithelial-to-mesenchymal transition (EMT). In the study conducted by Luyi Li et al, the researchers also questioned the…
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By Dr. Youngran ParkEndometriosis and its pro-fibrotic nature.
By Dr. Youngran Park
Endometriosis is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites. However, with advances in disease knowledge, several vital issues challenge this old definition. Especially, endometrial stromal and glands have been shown to represent only…
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